Predicted Winners in BOLD
Kirsten Flipkens (BEL) vs. Simona Halep (ROU)  – Flipkens is a solid player, but Halep should advance.
Kateryna Kozlova (UKR) vs. Venus Williams (USA)  – Venus is hard to predict in singles at this stage of her career, but I would think she should win.
I was 1 year out of undergraduate studies when Serena won this match
Serena Williams (USA)  vs. Ekaterina Makarova (RUS) – This is a lousy draw for Makarova and not great for Serena either. I think Serena wins, but Makarova is a player with legitimate quarterfinal potential who is facing the #1 seed out of the gate. Makarova also won gold in doubles, and doubles players troubled Serena in NY last year.
Denisa Allertova (CZE) vs. Ana Ivanovic (SRB)  – Ivanovic has been struggling. She may win this round, but barring improvement in her form Ana won’t be around too long.
Agnieszka Radwanska (POL)  vs. Jessica Pegula (USA) – Aga just won a title.
Katerina Siniakova (CZE) vs. Eugenie Bouchard (CAN) – Maybe?
Louisa Chirico (USA) vs. Anastasia Pavlyuchenkova (RUS) 
Pauline Parmentier (FRA) vs. Caroline Garcia (FRA) 
Karolina Pliskova (CZE)  vs. Sofia Kenin (USA) – Can Pliskova play like she did in Cincinnati?
Kurumi Nara (JPN) vs. Stefanie Voegele (SUI)
Nao Hibino (JPN) vs. Kristina Mladenovic (FRA)
Lucie Safarova (CZE) vs. Daria Gavrilova (AUS) – This is a tough draw for both players. Safarova’s recent singles results have not been setting the world on fire, but I think her experience makes the difference.
Camila Giorgi (ITA) vs. Samantha Stosur (AUS) 
Heather Watson (GBR) vs. Richel Hogenkamp (NED)
Naomi Broady (GBR) vs. Laura Robson (GBR) – How healthy is Robson?
Anett Kontaveit (EST) vs. Elena Vesnina (RUS) 
Mariana Duque-Mariño (COL) vs. Jelena Jankovic (SRB) – JJ could win this match.
Nicole Gibbs (USA) vs. Aleksandra Krunic (SRB)
Julia Goerges (GER) vs. Yanina Wickmayer (BEL)
Vitalia Diatchenko (RUS) vs. Timea Bacsinszky (SUI)  – Bacsinszky FTW
Montserrat Gonzalez (PAR) vs. Danka Kovinic (MNE)
Timea Babos (HUN)  vs. Barbara Haas (AUT)
Karin Knapp (ITA) vs. Johanna Larsson (SWE) – Does Knapp have enough steam to win this match?
Daria Kasatkina (RUS)  vs. Qiang Wang (CHN)
Shuai Zhang (CHN) vs. Ellen Perez (AUS)
Carla Suárez Navarro (ESP)  vs. Teliana Pereira (BRA) – Fear the backhand?
Antonia Lottner (GER) vs. Vania King (USA)
Kiki Bertens (NED)  vs. Ana Konjuh (CRO)
Shuai Peng (CHN) vs. Varvara Lepchenko (USA)
Lara Arruabarrena (ESP) vs. Yaroslava Shvedova (KAZ)
Laura Siegemund (GER)  vs. Patricia Maria Tig (ROU)
Annika Beck (GER) vs. Nadia Podoroska (ARG) – Can these other Germans join in Kerber’s 2016 fun?