Predicted Winners in BOLD
 Rafael Nadal (ESP) vs. Denis Istomin (UZB) – I could see Istomin push this to 4 sets, but Rafa likely wins in 3 or 4 sets.
Could this happen again?
 Novak Djokovic (SRB) vs. Jerzy Janowicz (POL) – Jerzy looked so promising in 2012 and 2013.
 Marin Cilic (CRO) vs Rogerio Dutra Silva (BRA) – Cilic conquered Cincinnati and is 12-1 in his past two US Opens.
 Jack Sock (USA) vs. Taylor Fritz (USA) – Jack Sock should win this match, but it is far from a lock.
 John Isner (USA) vs. [WC] Frances Tiafoe (USA) – Isner has been a bit out of sorts this summer, but I think she wins this match.
 Jo-Wilfried Tsonga (FRA) vs. [Q] Guido Andreozzi (ARG)
Thomaz Bellucci (BRA) vs. Andrey Kuznetsov (RUS)
 Pablo Cuevas (URU) vs Dudi Sela (ISR)
 Richard Gasquet (FRA) vs Kyle Edmund (GBR) – I am not sure if Gasquet is healthy.
[PR] Brian Baker (USA) vs. Federico Delbonis (ARG) – I may be picking with my heart more than my head here, but Baker could win this match.
Marcos Baghdatis (CYP) vs. Facundo Bagnis (ARG) – Baghdatis needs to not let this become a war of attrition.
 Lucas Pouille (FRA) vs. Mikhail Kukushkin (KAZ) – This could go either way.
Lukas Lacko (SVK) vs. [WC] Ernesto Escobedo (USA)
 Roberto Bautista Agut (ESP) vs Guillermo Garcia-Lopez (ESP) – If I had a ticket, I would park myself next to this match. This could be 5 sets of great rallies.
Sergiy Stakhovsky (UKR) vs. Gastao Elias (POR)
[Q] Mischa Zverev (GER) vs. Pierre-Hugues Herbert (FRA)
 Albert Ramos-Vinolas (ESP) vs [PR] Julien Benneteau (FRA)
Jiri Vesely (CZE) vs. [Q] Saketh Myneni (IND)
[WC] Bjorn Fratangelo (USA) vs. Guido Pella (ARG) – Tennis is better off with a Bjorn in it.
[Q] Jan Satral (CZE) vs. [WC] Mackenzie McDonald (USA)
 Benoit Paire (FRA) vs. Dusan Lajovic (SRB)
Adrian Mannarino (FRA) vs. [Q] Ryan Harrison (USA) – Harrison has a shot to win this match.
 Kevin Anderson (RSA) vs Yoshihito Nishioka (JPN)
[WC] James Duckworth (AUS) vs. Robin Haase (NED) – I have no idea on this match. Haase seems past his prime, but I can’t pick Duckworth.
 Martin Klizan (SVK) vs Mikhail Youzhny (RUS) – I am slightly leaning toward Youzhny here.
Stéphane Robert (FRA) vs. Andreas Seppi (ITA) – This should be a fun match that could go either way.
[Q] Marton Fucsovics (HUN) vs. Nicolas Almagro (ESP) – Can Almagro rediscover his firepower?
[Q] Guilherme Clezar (BRA) vs. [Q] Marco Chiudinelli (SUI)
 Gael Monfils (FRA) s. Gilles Muller (LUX) – I like Gael here, but this is a terrible draw for both players who have had nice 2016 seasons.
 Milos Raonic (CAN) vs Dustin Brown (GER) – This should be a fun match, but Milos really should win.
Jordan Thompson (AUS) vs. [Q] Steve Darcis (BEL)
Vasek Pospisil (CAN) vs. [LL] Jozef Kovalik (SVK) – If the lucky loser can return a few big serves, he will find himself in the 2nd round of a major.