Rod Laver Arena
 Rafael Nadal (ESP) vs. Laslo Djere (SRB) – Rafa rolls
 Stefanos Tsitsipas (GRE) vs. Gilles Simon (FRA) – This is a nightmare first round draw. Simon makes people play badly and hangs around. Still, Stefanos should win this match in 2021.
Margaret Court Arena
 Daniil Medvedev (RUS) vs. Vasek Pospisil (CAN) – Daniil will need to be ready to return well, but his amoeba tennis should prevail.
 Matteo Berrettini (ITA) vs. Kevin Anderson (RSA) – This should be an excellent match *Match of the Day*
John Cain Arena (Noon start)
 Andrey Rublev (RUS) vs. Yannick Hanfmann (GER)
 Alex de Minaur (AUS) vs. Tennys Sandgren (USA) – We shall see. Sandgren seems to play well in Oz.
 Roberto Bautista Agut (ESP) vs. Radu Albot (MDA)
 Casper Ruud (NOR) vs. Jordan Thompson (AUS)
 David Goffin (BEL) vs. Alexei Popyrin (AUS)
Soonwoo Kwon (KOR) vs. [WC] Thanasi Kokkinakis (AUS) Home sweet home?
 Hubert Hurkacz (POL) vs. Mikael Ymer (SWE)
 Fabio Fognini (ITA) vs. Pierre-Hugues Herbert (FRA)
Marco Cecchinato (ITA) vs. Mackenzie McDonald (USA)
Andreas Seppi (ITA) vs. Pablo Cuevas (URU) – I love this match, but unfortunately someone has to lose.
Jan-Lennard Struff (GER) vs. [WC] Christopher O’Connell (AUS)
Feliciano Lopez (ESP) vs. [WC] Tu Li (AUS) – A win for the old guys?
 Karen Khachanov (RUS) vs. [WC] Aleksandar Vukic (AUS)
 Daniel Evans (GBR) vs. Cameron Norrie (GBR)
Thiago Monteiro (BRA) vs. Andrej Martin (SVK)
Tommy Paul (AUS) vs. Nikoloz Basilashvili (GEO)
 Filip Krajinovic (SRB) vs. [LL] Robin Haase (NED)
Ilya Ivashka (BLR) vs. [LL] Roman Safiullin (RUS)
 Borna Coric (CRO) vs. Guido Pella (ARG)
Michael Mmoh (USA) vs. [Q] Viktor Troicki (SRB)
 Lorenzo Sonego (ITA) vs. Sam Querrey (USA)
Mario Vilella Martinez (ESP) vs. Tomas Machac (CZE)
Pablo Andujar (ESP) vs. Quentin Halys (FRA)
Roberto Carballes Baena (ESP) vs. Attila Balazs (HUN) – Viva Espana in these two matches!
Lloyd Harris (RSA) vs. [LL] Mikael Torpegaard (DEN) – Lucky losers are match tough and are playing with house money.
Henri Laaksonen (SUI) vs. Salvatore Caruso (ITA)
Carlos Alcaraz (ESP) vs. Botic Van de Zandschulp (NED)
Ricardas Berankis (LTU) vs [WC] Sumit Nagal (IND)