Predicted Winners in BOLD
Rod Laver Arena
 Karolina Pliskova (CZE) vs. Danielle Collins (USA) – These fast courts may give Pliskova her best shot at a major title since her near miss at the 2016 US Open.
 Ashleigh Barty (AUS) vs. [WC] Daria Gavrilova (AUS) – Aussie clash goes to the #1 seed
 Elina Svitolina (UKR) vs. Coco Gauff (USA) – An upset? Not sure
Margaret Court Arena
 Belinda Bencic (SUI) vs. Svetlana Kuznetsova (RUS) – Good on Kuzy for still battling, but I think Bencic wins.
 Sofia Kenin (USA) vs. Kaia Kanepi (EST) – This will be tricky for Kenin.
Jessica Pegula (USA) vs. [WC] Samantha Stosur (AUS) – One more round, for Sam? Probably not
John Cain Arena (Noon start)
 Anett Kontaveit (EST) vs. Heather Watson (GBR) – The courts play a factor here
1573 Arena (11 a.m.)
 Elise Mertens (BEL) vs. Zhu Lin (CHN)
 Jennifer Brady (USA) vs. Madison Brengle (USA)
[Q] Kaja Juvan (SLO) vs. [Q] Mayar Sherif (EGY) – One of these two will have a lot of ranking points after this qualifier showdown.
Shelby Rogers (USA) vs. Olga Danilovic (SRB)
Kristina Mladenovic (FRA) vs. Mao Hibino (JPN)
 Donna Vekic (CRO) vs. Nadia Podoroska (ARG)
 Karolina Mucova (CZE) vs Mona Barthel (GER)
 Yulia Putintseva (KAZ) vs. Alison Van Uytvanck (BEL)
 Ekaterina Alexandrova (RUS) vs. Barbora Krejcikova (CZE)