Predicted Winners in BOLD

Rod Laver Arena  (11 a.m. start)

[4] Daniil Medvedev (RUS) vs. [28] Filip Krajinovic (SRB) 

[2] Rafael Nadal (ESP) vs. Cameron Norrie (GBR) – Rafa and Daniil ought to advance.

Margaret Court Arena

 [7] Andrey Rublev (RUS) vs. Feliciano Lopez (ESP) – Rublev will need to return well and pass when Lopez comes forward. I think he does that well enough to win in 4 good sets.
[16] Fabio Fognini (ITA) vs. [21] Alex de Monaur (ESP) – I like Fognini to advance.

John Cain Arena (Noon start)

[5] Stefanos Tsitsipas (GRE) vs. Mikael Ymer (SWE) – Ymer has had a great run and Tsitsipas might be leg weary from his 2nd round battle. Still, Tsitsipas should advance.
[9] Matteo Berrettini (ITA) vs. [19] Karen Khachanov (RUS) – The winner of this match might move into dark horse status.

1573 Arena

[24] Casper Ruud (NOR) vs. Radu Albot (MDA)

Court 3

Mackenzie McDonald (USA) vs. Lloyd Harris (RSA) – Someone is moving forward to a lot of computer points.